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Septin4tm1Ksh
Targeted Allele Detail
Summary
Symbol: Septin4tm1Ksh
Name: septin 4; targeted mutation 1, Makoto Kinoshita
MGI ID: MGI:3574373
Synonyms: Sept4-
Gene: Septin4  Location: Chr11:87457515-87481365 bp, + strand  Genetic Position: Chr11, 52.14 cM
Alliance: Septin4tm1Ksh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:96670
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129X1/SvJ
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: The entire coding sequence, exons 2-10, was replaced with a neo. Absense of protein was confirmed by immunoblot of mutant testis. (J:96670)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 2 assay results
In Structures Affected by this Mutation: 1 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Septin4 Mutation:  42 strains or lines available
References
Original:  J:96670 Ihara M, et al., Cortical organization by the septin cytoskeleton is essential for structural and mechanical integrity of mammalian spermatozoa. Dev Cell. 2005 Mar;8(3):343-52
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory