Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(Sftpc-cre)1Blh
Name:	transgene insertion 1, Brigid L Hogan
MGI ID:	MGI:3574949
Synonyms:	CreSftpc, Sftpc-cre, SPC-Cre
Transgene:	Tg(Sftpc-cre)1Blh  Location: unknown
Alliance:	Tg(Sftpc-cre)1Blh page

Strain of Origin:

(C57BL/6 x DBA/2)F2

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Sftpc-cre)1Blh expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Sftpc   Mutation details: The Sftpc promoter was cloned upstream of the rabbit beta-globin intron 2, followed by cre recombinase, an NLS and the beta-globin polyA signal. Sftpc is active in the lung endoderm beginning at E10.5. (J:91317, J:97215)

Activity:	Tissue activity of this recombinase allele
Driver:	Sftpc (species not specified) Summary of all recombinase alleles driven by Sftpc. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	179 assay results 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	2 anatomical structure(s)

List all tumor models in MMHCdb carrying Tg(Sftpc-cre)1Blh

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:91317 Okubo T, et al., Hyperactive Wnt signaling changes the developmental potential of embryonic lung endoderm. J Biol. 2004;3(3):11
All:	68 reference(s)