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Ptprmtm1Mfbg
Targeted Allele Detail
Summary
Symbol: Ptprmtm1Mfbg
Name: protein tyrosine phosphatase receptor type M; targeted mutation 1, Martijn F B G Gebbink
MGI ID: MGI:3575002
Synonyms: RPTPmu-, RPTPmu-LacZ-
Gene: Ptprm  Location: Chr17:66973942-67661452 bp, - strand  Genetic Position: Chr17, 37.88 cM
Alliance: Ptprmtm1Mfbg page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:97231
Parent Cell Line:  E14 (ES Cell)
Strain of Origin:  129P2/OlaHsd
Mutation
description
Allele Type:    Targeted (Null/knockout, Reporter)
Mutation:    Insertion
 
Mutation detailsLacZ and a hygro cassette were inserted at the ATG such that betagalactosidase was expressed by the endogenous regulatory sequences. Part of the first exon was deleted. (J:97231)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 89 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ptprm Mutation:  62 strains or lines available
References
Original:  J:97231 Koop EA, et al., Receptor protein tyrosine phosphatase mu expression as a marker for endothelial cell heterogeneity; analysis of RPTPmu gene expression using LacZ knock-in mice. Int J Dev Biol. 2003 Jun;47(5):345-54
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory