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Tg(Pomc1-cre)1Gsb
Transgene Detail
Summary
Symbol: Tg(Pomc1-cre)1Gsb
Name: transgene insertion 1, Gregory S Barsh
MGI ID: MGI:3576071
Synonyms: TgPomcCre
Transgene: Tg(Pomc1-cre)1Gsb  Location: unknown  
Alliance: Tg(Pomc1-cre)1Gsb page
Transgene
origin
Strain of Origin:  FVB/N
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pomc1-cre)1Gsb expression driven by 1 gene
 
Mutation details: Cre recombinase cDNA with an IVSpA sequence was placed within exon 2 of Pomc1, immediately upstream of the normal translational start site in a BAC clone. Cre was expressed in the lateral portion of the arcuate nucleus of mutant brains. (J:97407)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pomc (species not specified)
Summary of all recombinase alleles driven by Pomc.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 7 assay results
2 RNA-Seq or microarray experiment(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:97407 Xu AW, et al., PI3K integrates the action of insulin and leptin on hypothalamic neurons. J Clin Invest. 2005 Apr 1;115(4):951-958
All:  37 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory