Tg(ACTA1-cre/ERT2)97.16Mtz Transgene Detail MGI Mouse (MGI:3576667)

Tg(ACTA1-cre/ERT2)97.16Mtz
Transgene Detail

Summary

Symbol:	Tg(ACTA1-cre/ERT2)97.16Mtz
Name:	transgene insertion 97.16, Daniel Metzger
MGI ID:	MGI:3576667
Synonyms:	Actin-cre, HSA-Cre-Er^T2, HSA-Cre-ER^T2(tg/0), Tg(ACTA1-cre)97.16Mtz
Transgene:	Tg(ACTA1-cre/ERT2)97.16Mtz Location: unknown
Alliance:	Tg(ACTA1-cre/ERT2)97.16Mtz page

Transgene
origin

Strain of Origin:

B6SJLF1

Transgene
description

Transgene Type:

Transgenic (Inducible, Recombinase)

Inducer:

tamoxifen

Mutation:

Insertion

Tg(ACTA1-cre/ERT2)97.16Mtz expression driven by 1 gene

Mutation details: Tamoxifen-dependent Cre-ER^T2 recombinase cDNA was inserted at the human skeletal alpha-actin (ACTA1) transcriptional initiation codon in exon 2 of a 90-kb HSA genomic segment contained in a PAC. Five copies were integrated into the genome in this line. (J:97313)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	ACTA1 (human) Summary of all recombinase alleles driven by ACTA1. Comparative matrix view of recombinase activities Alliance human ACTA1 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Disease models

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

Original:	J:97313 Schuler M, et al., Temporally controlled targeted somatic mutagenesis in skeletal muscles of the mouse. Genesis. 2005 Apr;41(4):165-70
All:	46 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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