Nfkbia<tm1Kbp> Targeted Allele Detail MGI Mouse (MGI:3577709)

Nfkbia^tm1Kbp
Targeted Allele Detail

Summary

Symbol:	Nfkbia^tm1Kbp
Name:	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha; targeted mutation 1, Klaus Pfeffer
MGI ID:	MGI:3577709
Synonyms:	ikba^f
Gene:	Nfkbia Location: Chr12:55536195-55539432 bp, - strand Genetic Position: Chr12, 24.0 cM, cytoband C1-C3
Alliance:	Nfkbia^tm1Kbp page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:97945
Parent Cell Line:	E14.1 (ES Cell)
Strain of Origin:	129P2/OlaHsd

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		LoxP sites were inserted to flank the promoter region and the first two exons. (J:97945)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Nfkbia Mutation:	19 strains or lines available

References

Original:	J:97945 Rupec RA, et al., Stroma-mediated dysregulation of myelopoiesis in mice lacking I kappa B alpha. Immunity. 2005 Apr;22(4):479-91
All:	11 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24