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Tbx20tm1.1Sev
Targeted Allele Detail
Summary
Symbol: Tbx20tm1.1Sev
Name: T-box 20; targeted mutation 1.1, Sylvia Evans
MGI ID: MGI:3579849
Synonyms: Tbx20-
Gene: Tbx20  Location: Chr9:24632108-24685580 bp, - strand  Genetic Position: Chr9, 10.25 cM
Alliance: Tbx20tm1.1Sev page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98516
Parent Cell Line:  SM1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details: Exon 2 was removed via cre-mediated recombination. RT-PCR analysis of mutant heart detected a new, shorter transcript resulting from the stop codon in exon 3 that was created by the excision of exon 2. (J:98516)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 8 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Tbx20 Mutation:  36 strains or lines available
References
Original:  J:98516 Cai CL, et al., T-box genes coordinate regional rates of proliferation and regional specification during cardiogenesis. Development. 2005 May;132(10):2475-87
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory