Summary | Transgene origin | Transgene description | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | Notes | References

Symbol:	Tg(Tyr-cre)3Gfk
Name:	transgene insertion 3, Graham F Kay
MGI ID:	MGI:3580525
Synonyms:	TEC3, TgN(TyrCre)3Gfk
Transgene:	Tg(Tyr-cre)3Gfk  Location: unknown
Alliance:	Tg(Tyr-cre)3Gfk page

Strain of Origin:

(C57BL/6 x CBA)F2 or (C57BL/6 x 129)F2

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(Tyr-cre)3Gfk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Note Not Specified Tyr   Mutation details: These transgenes express cre under the control of the tyrosinase promoter. Three lines were reported. Lines 1 and 2 include the full enhancer in addition to the promoter. Line 3 lacks the enhancer. Line 3 expresses cre solely in melanoblasts. (J:87271)

Activity:	Tissue activity of this recombinase allele
Driver:	Tyr (species not specified) Summary of all recombinase alleles driven by Tyr. Comparative matrix view of recombinase activities

View phenotypes and curated references for all genotypes (concatenated display).

List all tumor models in MMHCdb carrying Tg(Tyr-cre)3Gfk

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available

Original:	J:87271 Tonks ID, et al., Tyrosinase-Cre mice for tissue-specific gene ablation in neural crest and neuroepithelial-derived tissues. Genesis. 2003 Nov;37(3):131-8
All:	6 reference(s)