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Oclntm2Sts
Targeted Allele Detail
Summary
Symbol: Oclntm2Sts
Name: occludin; targeted mutation 2, Shoichiro Tsukita
MGI ID: MGI:3582579
Gene: Ocln  Location: Chr13:100633015-100689226 bp, - strand  Genetic Position: Chr13, 53.23 cM
Alliance: Oclntm2Sts page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:99467
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exon 3 was replaced with a floxed neo cassette via homologous recombination. RT-PCR and western blot analysis confirmed the absence of mRNA and protein. (J:99467)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 10 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ocln Mutation:  33 strains or lines available
References
Original:  J:99467 Saitou M, et al., Complex phenotype of mice lacking occludin, a component of tight junction strands. Mol Biol Cell. 2000 Dec;11(12):4131-42
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory