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Gabrg2tm2.1Geh
Targeted Allele Detail
Summary
Symbol: Gabrg2tm2.1Geh
Name: gamma-aminobutyric acid type A receptor, subunit gamma 2; targeted mutation 2.1, Gregg E Homanics
MGI ID: MGI:3582967
Gene: Gabrg2  Location: Chr11:41801030-41891684 bp, - strand  Genetic Position: Chr11, 24.8 cM
Alliance: Gabrg2tm2.1Geh page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:98560
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: The floxed exon 8 was deleted from Gabrg2tm2Geh mice by cre-mediated recombination using Tg(ACTB-cre)2Mrt mice. (J:98560)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Gabrg2 Mutation:  41 strains or lines available
References
Original:  J:98560 Chandra D, et al., GABAA receptor gamma2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines. BMC Neurosci. 2005 Apr 25;6(1):30
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory