Tg(Nphs2-cre)1Seq Transgene Detail MGI Mouse (MGI:3586451)

Tg(Nphs2-cre)1Seq
Transgene Detail

Summary

Symbol:	Tg(Nphs2-cre)1Seq
Name:	transgene insertion 1, Susan E Quaggin
MGI ID:	MGI:3586451
Synonyms:	Podocin-Cre, Tg(Nphs2-cre)1Nagy
Transgene:	Tg(Nphs2-cre)1Seq Location: unknown
Alliance:	Tg(Nphs2-cre)1Seq page

Transgene
origin

Germline Transmission:	Earliest citation of germline transmission: J:99607
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Transgene
description

Transgene Type:

Transgenic (Recombinase)

Mutation:

Insertion

Tg(Nphs2-cre)1Seq expression driven by 1 gene

Mutation details: The transgene expresses cre recombinase under the control of the murine podocin (Nphs2) promoter in podocytes of glomerulus. (J:99607)

Recombinase
activity

Activity:	Tissue activity of this recombinase allele
Driver:	Nphs2 (mouse) Summary of all recombinase alleles driven by Nphs2. Comparative matrix view of recombinase activities Alliance mouse Nphs2 gene page

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

Original:	J:99607 Belteki G, et al., Conditional and inducible transgene expression in mice through the combinatorial use of Cre-mediated recombination and tetracycline induction. Nucleic Acids Res. 2005;33(5):e51
All:	21 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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