Cd44<tm2Ugu> Targeted Allele Detail MGI Mouse (MGI:3588663)

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Cd44^tm2Ugu
Targeted Allele Detail

Summary | Mutation origin | Mutation description | Phenotypes | Find Mice (IMSR) | References

Summary

Symbol:	Cd44^tm2Ugu
Name:	CD44 antigen; targeted mutation 2, Ursula Gunthert
MGI ID:	MGI:3588663
Synonyms:	CD44v10-loxP
Gene:	Cd44 Location: Chr2:102641486-102732010 bp, - strand Genetic Position: Chr2, 54.13 cM
Alliance:	Cd44^tm2Ugu page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:100298
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation
description

Allele Type:		Targeted (Conditional ready, No functional change)
Mutation:		Insertion
		Mutation details: A loxP site was inserted 5' to exon v10 and a second loxP site was placed 3' to a neomycin cassette located 3' of exon v10. (J:108416)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Cd44 Mutation:	72 strains or lines available

References

Original:	J:100298 Spitz F, et al., Inversion-induced disruption of the Hoxd cluster leads to the partition of regulatory landscapes. Nat Genet. 2005 Aug;37(8):889-93
All:	3 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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