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Ndel1tm1.1Shr
Targeted Allele Detail
Summary
Symbol: Ndel1tm1.1Shr
Name: nudE neurodevelopment protein 1 like 1; targeted mutation 1.1, Shinji Hirotsune
MGI ID: MGI:3589465
Synonyms: Ndel1-, Ndel1ko(III)
Gene: Ndel1  Location: Chr11:68712260-68743961 bp, - strand  Genetic Position: Chr11, 42.09 cM
Alliance: Ndel1tm1.1Shr page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100552
Parent Cell Line:  TC1/TC-1 (ES Cell)
Strain of Origin:  129S6/SvEvTac
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion
 
Mutation details: Cre mediated recombination was used to remove exon III. Western blot of brain samples from E15.5 embryos failed to detect protein. (J:100552)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ndel1 Mutation:  40 strains or lines available
References
Original:  J:100552 Sasaki S, et al., Complete loss of Ndel1 results in neuronal migration defects and early embryonic lethality. Mol Cell Biol. 2005 Sep;25(17):7812-27
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory