About   Help   FAQ
Prkcgtm1(cre)Zfc
Targeted Allele Detail
Summary
Symbol: Prkcgtm1(cre)Zfc
Name: protein kinase C, gamma; targeted mutation 1, Zhou-Feng Chen
MGI ID: MGI:3603180
Synonyms: PKCgamma-Cre
Gene: Prkcg  Location: Chr7:3352038-3379615 bp, + strand  Genetic Position: Chr7, 1.93 cM
Alliance: Prkcgtm1(cre)Zfc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:100950
Parent Cell Line:  Other (see notes) (ES Cell)
Strain of Origin:  129S7/SvEvBrd
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Prkcgtm1(cre)Zfc expression driven by 1 gene
 
Mutation details: Cre recombinase cDNA and a PGK-neo were inserted at the ATG to replace the first two coding exons. Immunohistochemical staining demonstrated cre-expressing cells with high density in the cerebral cortex, hippocampus, amgdala and thalamus and with low density in the olfactory system, septal region, basal ganglia, hypothalamus, brainstem and spinal cord. (J:100950)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Prkcg (mouse)
Summary of all recombinase alleles driven by Prkcg.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Prkcg Mutation:  42 strains or lines available
Notes
ES cell line = "AB-2."
References
Original:  J:100950 Ding YQ, et al., Generation and characterization of the PKCgamma-Cre mouse line. Genesis. 2005 Sep;43(1):28-33
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory