Npm1<Gt(VICTR37)704Lex> Gene trapped Allele Detail MGI Mouse (MGI:3604210)

Npm1^{Gt(VICTR37)704Lex}
Gene trapped Allele Detail

Summary

Symbol:	Npm1^{Gt(VICTR37)704Lex}
Name:	nucleophosmin 1; gene trap 704, Lexicon Genetics
MGI ID:	MGI:3604210
Synonyms:	NPM^-, Npm1^{Gt(VICTR37)1Lex}
Gene:	Npm1 Location: Chr11:33102287-33113206 bp, - strand Genetic Position: Chr11, 19.21 cM
Alliance:	Npm1^{Gt(VICTR37)704Lex} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:101353
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Mutation
description

Allele Type:		Gene trapped (Null/knockout, Reporter)
Mutation:		Insertion of gene trap vector
		Mutation details: The VICTR37 gene trap vector containing an IRES-Betageo cassette integrated into intron 1. Western blot failed to detect protein in mutant whole embryo lysates. (J:101353)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Structures Affected by this Mutation:

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Npm1 Mutation:	36 strains or lines available

References

Original:	J:101353 Colombo E, et al., Nucleophosmin is required for DNA integrity and p19Arf protein stability. Mol Cell Biol. 2005 Oct;25(20):8874-86
All:	1 reference(s)

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