Mkks<Gt(OST367255)Lex> Gene trapped Allele Detail MGI Mouse (MGI:3608879)

Mkks^{Gt(OST367255)Lex}
Gene trapped Allele Detail

Summary

Symbol:	Mkks^{Gt(OST367255)Lex}
Name:	McKusick-Kaufman syndrome; gene trap OST367255, Lexicon Genetics
MGI ID:	MGI:3608879
Synonyms:	Bbs6^-, Mkks^-, Mkks^{Gt(Betageo-BTK)705Lex}
Gene:	Mkks Location: Chr2:136715700-136733309 bp, - strand Genetic Position: Chr2, 67.64 cM
Alliance:	Mkks^{Gt(OST367255)Lex} page

Mutation
origin

Mutant Cell Line:	OST367255
Germline Transmission:	Earliest citation of germline transmission: J:102697
Parent Cell Line:	Lex-1 (ES Cell)
Strain of Origin:	129S5/SvEvBrd
Project Collection:	Lexicon

Mutation
description

Allele Type:

Gene trapped (Null/knockout, Reporter)

Mutation:

Insertion of gene trap vector

Mutation details: A gene trap vector consisting of LTR sites flanking a Beta-geo cassette containing a splice acceptor integrated into the intron between exon 1 and 2. RT-PCR confirmed absence of RNA. (J:102697)

Sequence Tags:

Sequence tag details (1 tag)

Genome Context:

Genome Browser view of this mutation

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Expression

In Mice Carrying this Mutation:	23 assay results
In Structures Affected by this Mutation:	3 anatomical structure(s)

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available Cell Lines: 0 lines available
Carrying any Mkks Mutation:	27 strains or lines available

References

Original:	J:102697 Ross AJ, et al., Disruption of Bardet-Biedl syndrome ciliary proteins perturbs planar cell polarity in vertebrates. Nat Genet. 2005 Oct;37(10):1135-40
All:	7 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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