Gt(ROSA)26Sor<tm1(sb11)Njen> Targeted Allele Detail MGI Mouse (MGI:3608906)

Gt(ROSA)26Sor^{tm1(sb11)Njen}
Targeted Allele Detail

Summary

Symbol:	Gt(ROSA)26Sor^{tm1(sb11)Njen}
Name:	gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Nancy A Jenkins
MGI ID:	MGI:3608906
Synonyms:	Rosa26-SB11, RosaSB, RosaSBase
Gene:	Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
Alliance:	Gt(ROSA)26Sor^{tm1(sb11)Njen} page

Mutation
origin

Germline Transmission:	Earliest citation of germline transmission: J:102234
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Mutation
description

Allele Type:		Targeted (Transposase)
Mutation:		Insertion
		Mutation details: An expression cassette containing the engrailed 2 splice acceptor, SB11 transposase cDNA followed by an SV40 polyA signal was inserted into the locus. Western blot confirmed the expression of the SB11 transposase in mutant mice. (J:102234)

Phenotypes

View phenotypes and curated references for all genotypes (concatenated display).

Tumor Data

List all tumor models in MMHCdb carrying Gt(ROSA)26Sor^{tm1(sb11)Njen}

Find Mice (IMSR)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available Cell Lines: 0 lines available
Carrying any Gt(ROSA)26Sor Mutation:	993 strains or lines available

References

Original:	J:102234 Dupuy AJ, et al., Mammalian mutagenesis using a highly mobile somatic Sleeping Beauty transposon system. Nature. 2005 Jul 14;436(7048):221-6
All:	30 reference(s)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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