Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol: Sox9tm3(cre)Crm Name: SRY (sex determining region Y)-box 9; targeted mutation 3, Benoit de Crombrugghe MGI ID: MGI:3608931 Synonyms: Sox9-Cre, Sox9-IRES-Cre Gene: Sox9  Location: Chr11:112673050-112678586 bp, + strand  Genetic Position: Chr11, 77.27 cM Alliance: Sox9tm3(cre)Crm page

Rib fusion phenotype is enhanced in Gnai3tm1Lbi/Gnai3tm1Lbi mice by loss of Gnai2 in cartilage Show the 1 phenotype image(s) involving this allele.

Germline Transmission:	Earliest citation of germline transmission: J:102495
Parent Cell Line:	AB1 (ES Cell)
Strain of Origin:	129S7/SvEvBrd-Hprt1+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Sox9tm3(cre)Crm expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Sox9 (MGI:98371)   Mutation details: An IRES-Cre-pA sequence with an FRT-flanked PGK-neo-bpA cassette was inserted into the 3' UTR in exon 3. (J:102495)

Activity:	Tissue activity of this recombinase allele
Driver:	Sox9 (mouse) Summary of all recombinase alleles driven by Sox9. Alliance mouse Sox9 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

75 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sox9 Mutation:	33 strains or lines available

Original:	J:102495 Akiyama H, et al., Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14665-70
All:	41 reference(s)