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Sp7tm2Crm
Targeted Allele Detail
Summary
Symbol: Sp7tm2Crm
Name: Sp7 transcription factor 7; targeted mutation 2, Benoit de Crombrugghe
MGI ID: MGI:3608932
Synonyms: Osxflox
Gene: Sp7  Location: Chr15:102265038-102275498 bp, - strand  Genetic Position: Chr15, 57.51 cM
Alliance: Sp7tm2Crm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:102495
Parent Cell Line:  AB1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: LoxP sites flanked exon 2. An FRT-flanked PGK-neo and IRES-EGFP-pA cassette were inserted at the second loxP site and subsequently removed by crossing with FLP recombinase expressing mice. (J:102495)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 5 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Sp7 Mutation:  21 strains or lines available
References
Original:  J:102495 Akiyama H, et al., Osteo-chondroprogenitor cells are derived from Sox9 expressing precursors. Proc Natl Acad Sci U S A. 2005 Oct 11;102(41):14665-70
All:  22 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory