Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Find Mice (IMSR) | Notes | References

Symbol:	Meox1tm1(cre)Jpa
Name:	mesenchyme homeobox 1; targeted mutation 1, Juha Partanen
MGI ID:	MGI:3611205
Synonyms:	Meox1Cre21, Mox1cre
Gene:	Meox1  Location: Chr11:101768336-101785200 bp, - strand  Genetic Position: Chr11, Syntenic
Alliance:	Meox1tm1(cre)Jpa page

Germline Transmission:	Earliest citation of germline transmission: J:102739
Parent Cell Line:	R1 (ES Cell)
Strain of Origin:	(129X1/SvJ x 129S1/Sv)F1-Kitl+

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Meox1tm1(cre)Jpa expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Meox1 (MGI:103220)   Mutation details: A cassette containing a splice acceptor, an IRES-EGFP-cre, the pA sequence, and a kanamycin/neomycin resistance gene was inserted into the locus. Cre expression was expected in the presomatic and somatic mesoderm. EGFP activity was not detected in mutant embryos between E9.5-11.5, possibly due to a low level of expression of the EGFP0cre fusion protein mediated by the IRES sequence. (J:102739)

Activity:	Tissue activity of this recombinase allele
Driver:	Meox1 (mouse) Summary of all recombinase alleles driven by Meox1. Comparative matrix view of recombinase activities Alliance mouse Meox1 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

60 assay results

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Meox1 Mutation:	17 strains or lines available

Original:	J:102739 Jukkola T, et al., Meox1Cre: a mouse line expressing Cre recombinase in somitic mesoderm. Genesis. 2005 Nov;43(3):148-53
All:	7 reference(s)