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Cfhr2 Gene Detail
Summary
  • Symbol
    Cfhr2
  • Name
    complement factor H-related 2
  • Synonyms
    FHR-B
  • Feature Type
    protein coding gene
  • IDs
    MGI:3611575
    NCBI Gene: 545366
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:139738030-139786437 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 61.62 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    957 from dbSNP Build 142
  • Strain Annotations
    11
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3611575
 protein coding gene Chr1:139731905-139786456 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016558
 protein coding gene Chr1:143932015-144154409 (-)
A/J MGP_AJ_G0016540
 protein coding gene Chr1:138312546-138366130 (-)
AKR/J MGP_AKRJ_G0016505
 protein coding gene Chr1:142488651-142824523 (-)
BALB/cJ MGP_BALBcJ_G0016501
 protein coding gene Chr1:138641312-138745001 (-)
C3H/HeJ no annotation
C57BL/6NJ MGP_C57BL6NJ_G0016961
 protein coding gene Chr1:148939750-149055332 (-)
CAROLI/EiJ no annotation
CAST/EiJ no annotation
CBA/J MGP_CBAJ_G0016299
 protein coding gene Chr1:154054342-154109670 (-)
DBA/2J MGP_DBA2J_G0016405
 protein coding gene Chr1:137192804-137365489 (-)
FVB/NJ no annotation
LP/J MGP_LPJ_G0016476
 protein coding gene Chr1:145067856-145117990 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016428
 protein coding gene Chr1:159507718-159813825 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0016996
 protein coding gene Chr1:142146788-142618040 (-)
PWK/PhJ no annotation
SPRET/EiJ no annotation
WSB/EiJ no annotation



Homology
more
  • Human Ortholog
    CFHR3, complement factor H related 3
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CFHR3, complement factor H related 3
  • Synonyms
    CFHL3, DOWN16, FHR-3, FHR3, HLF4
  • Links
    NCBI Gene ID: 10878
    neXtProt AC: NX_Q02985
    UniProt: Q02985

  • Chr Location
    1q31.3; chr1:196774813-196795407 (+)  GRCh38
Human Diseases
more
  • Diseases
    2 with human CFHR3 associations

Human Disease Mouse Models
      
IDs
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    6
  • GO References
    2
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    18
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 545366 NCBI Gene Model | MGI Sequence Detail 48408 C57BL/6J ±  kb
transcript NM_001025575 RefSeq | MGI Sequence Detail 1619 C57BL/6  
polypeptide NP_001020746 RefSeq | MGI Sequence Detail 332 C57BL/6  
For the selected sequence
Protein
Information
less
  • UniProt
    5 Sequences
  • InterPro Domains
    IPR051503 Complement System Regulators and Virion Entry Mediators
    IPR000436 Sushi/SCR/CCP domain
    IPR035976 Sushi/SCR/CCP superfamily
Molecular
Reagents
less
  • All nucleic 18
    cDNA 18

    Microarray probesets 5
References
more
  • Summaries
    All 23
    Gene Ontology 2
    Phenotypes 5
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:244983 Schultz NG, et al., The Genetic Basis of Baculum Size and Shape Variation in Mice. G3 (Bethesda). 2016 May 03;6(5):1141-51
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory