P2rx4tm1Ando
Targeted Allele Detail
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| Symbol: |
P2rx4tm1Ando |
| Name: |
purinergic receptor P2X, ligand-gated ion channel 4; targeted mutation 1, Joji Ando |
| MGI ID: |
MGI:3612982 |
| Synonyms: |
P2rx4- |
| Gene: |
P2rx4 Location: Chr5:122845607-122867801 bp, + strand Genetic Position: Chr5, 62.53 cM
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| Alliance: |
P2rx4tm1Ando page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:104459
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| Parent Cell Line: |
Not Specified (ES Cell)
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| Strain of Origin: |
Not Specified
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Intragenic deletion
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Mutation details: Exons 3-5 were replaced by a neomycin resistance cassette flanked by two loxP sites and the neo cassette was subsequently removed with cre recombinase. Northern blot failed to detect transcript in mutant pulmonary microvessel endothelial cells. Protein was not detected by immunological assay.
(J:104459)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any P2rx4 Mutation: |
26 strains or lines available
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| Original: |
J:104459 Yamamoto K, et al., Impaired flow-dependent control of vascular tone and remodeling in P2X4-deficient mice. Nat Med. 2006 Jan;12(1):133-7 |
| All: |
7 reference(s) |
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Analysis Tools
