P2ry2tm1Bhk
Targeted Allele Detail
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| Symbol: |
P2ry2tm1Bhk |
| Name: |
purinergic receptor P2Y, G-protein coupled 2; targeted mutation 1, Beverly Koller |
| MGI ID: |
MGI:3613160 |
| Synonyms: |
P2ry2tm1Bouc, P2Y2-, P2Y2-R- |
| Gene: |
P2ry2 Location: Chr7:100645775-100661260 bp, - strand Genetic Position: Chr7, 54.47 cM, cytoband F1
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| Alliance: |
P2ry2tm1Bhk page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:57617
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| Parent Cell Line: |
E14TG2a (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A neomycin selection cassette replaced a genomic fragment corresponding to base pairs 552 - 1149 of the published cDNA. Northern blot analysis on RNA derived from kidney of homozygous mice confirmed that no detectable transcript is expressed from this allele.
(J:57617)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Original: |
J:57617 Homolya L, et al., Nucleotide-regulated calcium signaling in lung fibroblasts and epithelial cells from normal and P2Y(2) receptor (-/-) mice. J Biol Chem. 1999 Sep 10;274(37):26454-60 |
| All: |
68 reference(s) |
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Analysis Tools
