Hoxd1tm1Ddu
Targeted Allele Detail
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| Symbol: |
Hoxd1tm1Ddu |
| Name: |
homeobox D1; targeted mutation 1, Denis Duboule |
| MGI ID: |
MGI:3616015 |
| Synonyms: |
L11, TgH(d1/lac)Ge |
| Gene: |
Hoxd1 Location: Chr2:74593324-74595486 bp, + strand Genetic Position: Chr2, 44.13 cM
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| Alliance: |
Hoxd1tm1Ddu page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:70547
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| Parent Cell Line: |
D3 (ES Cell)
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| Strain of Origin: |
129S2/SvPas
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| Allele Type: |
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Targeted (Null/knockout, Reporter) |
| Mutation: |
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Insertion
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Mutation details: This allele was created in the same ES cells used to create Hoxdtm2.1Ddu and thus has a loxP site located 5' of Hoxd13. A lacZ reporter sequence followed by a PGKneo selection cassette was inserted into exon 2. In vitro cre expression removed the selection cassette only. The resulting fusion protein expressed all but the most C-terminal 25 amino acids.
(J:70547)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Hoxd1 Mutation: |
16 strains or lines available
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| Original: |
J:70547 Zakany J, et al., Localized and transient transcription of Hox genes suggests a link between patterning and the segmentation clock. Cell. 2001 Jul 27;106(2):207-17 |
| All: |
1 reference(s) |
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Analysis Tools
