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Mir181b-1 Gene Detail
Summary
  • Symbol
    Mir181b-1
  • Name
    microRNA 181b-1
  • Synonyms
    mir 181b-1, Mirn181b-1, mmu-mir-181b-1
  • Feature Type
    miRNA gene
  • IDs
    MGI:3618735
    NCBI Gene: 723890
  • Member of
    Mirc14 cluster
  • Alliance
    gene page
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:137894377-137894456 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 60.68 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    131 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3618735
 miRNA gene Chr1:137894377-137894456 (+)
129S1/SvImJ MGP_129S1SvImJ_G0007664
 miRNA gene Chr1:141968512-141968591 (+)
A/J MGP_AJ_G0007659
 miRNA gene Chr1:136480244-136480323 (+)
AKR/J MGP_AKRJ_G0007633
 miRNA gene Chr1:140576244-140576323 (+)
BALB/cJ MGP_BALBcJ_G0007637
 miRNA gene Chr1:136812937-136813016 (+)
C3H/HeJ MGP_C3HHeJ_G0007582
 miRNA gene Chr1:140676652-140676731 (+)
C57BL/6NJ MGP_C57BL6NJ_G0007812
 miRNA gene Chr1:146957786-146957865 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0006976
 miRNA gene Chr1:129534693-129534772 (+)
CAST/EiJ MGP_CASTEiJ_G0007478
 miRNA gene Chr1:139832946-139833024 (+)
CBA/J MGP_CBAJ_G0007557
 miRNA gene Chr1:152026469-152026548 (+)
DBA/2J MGP_DBA2J_G0007591
 miRNA gene Chr1:135463451-135463530 (+)
FVB/NJ MGP_FVBNJ_G0007605
 miRNA gene Chr1:134119117-134119196 (+)
LP/J MGP_LPJ_G0007670
 miRNA gene Chr1:143076980-143077059 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0007579
 miRNA gene Chr1:157687788-157687867 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0007812
 miRNA gene Chr1:140346307-140346386 (+)
PWK/PhJ MGP_PWKPhJ_G0007411
 miRNA gene Chr1:134551137-134551216 (+)
SPRET/EiJ MGP_SPRETEiJ_G0007313
 miRNA gene Chr1:139330900-139330979 (+)
WSB/EiJ MGP_WSBEiJ_G0007546
 miRNA gene Chr1:140377791-140377870 (+)



Homology
more
  • Human Ortholog
    MIR181B1, microRNA 181b-1
  • Vertebrate Orthologs
    1
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    MIR181B1, microRNA 181b-1
  • Synonyms
    mir-181b-1, MIRN181B1
  • Links
    NCBI Gene ID: 406955

  • Chr Location
    chr1:198858873-198858982 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    3
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Genomic Mutations
    3 involving Mir181b-1
  • Find Mice (IMSR)
    1 strains or lines available
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    710
  • Tissues
    4
  • Literature Summary
    7
Sequences &
Gene Models
less
  • All Sequences
    23
  • RefSeq
    1
Representative SequencesLengthStrain/SpeciesFlank
genomic 723890 NCBI Gene Model | MGI Sequence Detail 80 C57BL/6J ±  kb
transcript NR_029820 RefSeq | MGI Sequence Detail 80 C57BL/6  
For the selected sequence
Molecular
Reagents
less
  • All nucleic 2
    Primer pair 1
    Other 1
Other Database
Links
less
miRBase MI0000723
References
more
  • Summaries
    All 37
    Developmental Gene Expression 7
    Gene Ontology 3
    Phenotypes 4
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:338558 Akiyoshi K, et al., Adenosine A(2A) Receptor Regulates microRNA-181b Expression in Aorta: Therapeutic Implications for Large-Artery Stiffness. J Am Heart Assoc. 2023 Jul 18;12(14):e028421
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/29/2024
MGI 6.24 		The Jackson Laboratory