Rad51btm1Kmic
Targeted Allele Detail
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| Symbol: |
Rad51btm1Kmic |
| Name: |
RAD51 paralog B; targeted mutation 1, Eric B Kmiec |
| MGI ID: |
MGI:3621480 |
| Synonyms: |
muREC2/RAD51L1- |
| Gene: |
Rad51b Location: Chr12:79344056-79861464 bp, + strand Genetic Position: Chr12, 35.51 cM
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| Alliance: |
Rad51btm1Kmic page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:58601
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| Parent Cell Line: |
J1 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: An IRES-beta geo expression cassette was inserted into exon 2. A fusion transcript is expressed from this allele that consists of the inserted sequences from the expression cassette. This transcript cannot express normal protein due to the inclusion of a stop codon, resulting in a shift of all three reading frames.
(J:58601)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rad51b Mutation: |
25 strains or lines available
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| Original: |
J:58601 Shu Z, et al., Disruption of muREC2/RAD51L1 in mice results in early embryonic lethality which can Be partially rescued in a p53(-/-) background. Mol Cell Biol. 1999 Dec;19(12):8686-93 |
| All: |
1 reference(s) |
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Analysis Tools
