Fgb Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:65092 Ishiguro K, et al., Complete antithrombin deficiency in mice results in embryonic lethality. J Clin Invest. 2000 Oct;106(7):873-8
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:3624334
Gene symbol:	Fgb
Gene name:	fibrinogen beta chain

Antibody:	anti-fibrin(ogen)
Detection system:	Secondary antibody coupled to biotin
Assay notes:	Antibody detects all three fibrinogen polypeptides, Fga, Fgb, and Fgg.

Results

3b ©

Specimen 3b: embryonic day 15.5 (more

)

Structure	Level	Pattern	Image	Note
TS23: cardiac muscle tissue	Absent		3b

3d ©

3e ©

3f ©

Specimen 3d,e,f: embryonic day 15.5; Serpinc1^tm1Sai/Serpinc1^tm1Sai (more

)
Note: e and f are magnifications of the areas indicated in d.

Structure	Level	Pattern	Image	Note
TS23: cardiac muscle tissue	Present		3f , 3d , 3e
TS23: liver	Present	Regionally restricted	3e , 3f , 3d	Expression is in the sinusoids and not in the central veins.

4b ©

Specimen 4b: embryonic day 14.5; Serpinc1^tm1Sai/Serpinc1^tm1Sai (more

)

Structure	Level	Pattern	Image	Note
TS22: cardiac muscle tissue	Present		4b

5b ©

Specimen 5b: embryonic day 16.5; Serpinc1^tm1Sai/Serpinc1^tm1Sai (more

)

Structure	Level	Pattern	Image	Note
TS24: head	Absent		5b

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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