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Krt12tm3(cre)Wwk
Targeted Allele Detail
Summary
Symbol: Krt12tm3(cre)Wwk
Name: keratin 12; targeted mutation 3, Winston W Y Kao
MGI ID: MGI:3624816
Synonyms: K12Cre, Krt12-Cre, Krt12Cre
Gene: Krt12  Location: Chr11:99306492-99313085 bp, - strand  Genetic Position: Chr11, 62.92 cM
Alliance: Krt12tm3(cre)Wwk page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108338
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Krt12tm3(cre)Wwk expression driven by 1 gene
 
Mutation details: An IRES-cre minigene was inserted into the site immediately behind the stop codon in exon 8. The mutant allele encodes a bicistronic mRNA with cre recombinase being under the control of the endogenous regulatory sequences. (J:108338, J:164088)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Krt12 (mouse)
Summary of all recombinase alleles driven by Krt12.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Krt12 Mutation:  24 strains or lines available
References
Original:  J:108338 Tanifuji-Terai N, et al., Expression of keratin 12 and maturation of corneal epithelium during development and postnatal growth. Invest Ophthalmol Vis Sci. 2006 Feb;47(2):545-51
All:  7 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory