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Bmp7tm6(cre)Rob
Targeted Allele Detail
Summary
Symbol: Bmp7tm6(cre)Rob
Name: bone morphogenetic protein 7; targeted mutation 6, Elizabeth J Robertson
MGI ID: MGI:3626288
Synonyms: Bmp7cre
Gene: Bmp7  Location: Chr2:172709805-172782114 bp, - strand  Genetic Position: Chr2, 95.54 cM
Alliance: Bmp7tm6(cre)Rob page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:108109
Parent Cell Line:  CCE/EK.CCE (ES Cell)
Strain of Origin:  129S/SvEv-Gpi1c
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Bmp7tm6(cre)Rob expression driven by 1 gene
 
Mutation details: A cassette containing an IRES-cre and FRT-flanked hygro was inserted into exon 1 of the locus. The hygro was removed via FLP mediated recombination. (J:108109)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Bmp7 (mouse)
Summary of all recombinase alleles driven by Bmp7.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 81 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Bmp7 Mutation:  37 strains or lines available
References
Original:  J:108109 Oxburgh L, et al., TGFbeta superfamily signals are required for morphogenesis of the kidney mesenchyme progenitor population. Development. 2004 Sep;131(18):4593-605
All:  4 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory