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Abcb7tm1Mdf
Targeted Allele Detail
Summary
Symbol: Abcb7tm1Mdf
Name: ATP-binding cassette, sub-family B member 7; targeted mutation 1, Mark D Fleming
MGI ID: MGI:3628654
Gene: Abcb7  Location: ChrX:103324263-103457462 bp, - strand  Genetic Position: ChrX, 46.58 cM, cytoband C-D
Alliance: Abcb7tm1Mdf page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:106838
Parent Cell Line:  J1 (ES Cell)
Strain of Origin:  129S4/SvJae
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: LoxP sites were inserted into the locus to flank exons 9 and 10. Transient cre expression removed a neomycin resistance cassette included in the vector. (J:106838)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Abcb7 Mutation:  13 strains or lines available
References
Original:  J:106838 Pondarre C, et al., The mitochondrial ATP-binding cassette transporter Abcb7 is essential in mice and participates in cytosolic iron-sulfur cluster biogenesis. Hum Mol Genet. 2006 Mar 15;15(6):953-64
All:  5 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory