Pth1rtm4Hmk
Targeted Allele Detail
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| Symbol: |
Pth1rtm4Hmk |
| Name: |
parathyroid hormone 1 receptor; targeted mutation 4, Henry M Kronenberg |
| MGI ID: |
MGI:3628795 |
| Synonyms: |
PTHRD |
| Gene: |
Pth1r Location: Chr9:110551153-110576213 bp, - strand Genetic Position: Chr9, 60.56 cM, cytoband F
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| Alliance: |
Pth1rtm4Hmk page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:108984
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| Parent Cell Line: |
J1 (ES Cell)
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| Strain of Origin: |
129S4/SvJae
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| Allele Type: |
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Targeted (Null/knockout) |
| Mutation: |
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Insertion
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Mutation details: A targeting vector was designed to mutate the EKKY in the second intracellular loop to DSEL. A neomycin gene inserted into the intron between exons E1 and E2 was subsequently removed via transient cre expression.
(J:108984)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Pth1r Mutation: |
29 strains or lines available
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| Original: |
J:108984 Guo J, et al., The PTH/PTHrP receptor can delay chondrocyte hypertrophy in vivo without activating phospholipase C. Dev Cell. 2002 Aug;3(2):183-94 |
| All: |
3 reference(s) |
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Analysis Tools
