Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Tg(ITGAM-cre)2781Gkl
Name:	transgene insertion 2781, George Kollias
MGI ID:	MGI:3629092
Synonyms:	CD11b-Cre, Tg(ITGAM-cre)1Dwc
Transgene:	Tg(ITGAM-cre)2781Gkl  Location: unknown
Alliance:	Tg(ITGAM-cre)2781Gkl page

Strain of Origin:

(CBA x C57BL/6)F1

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(ITGAM-cre)2781Gkl expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human ITGAM (3684) Itgam  (MGI:96607)   Mutation details: A 1.7 kb DNA fragment of the human integrin alpha M promoter was used to drive expression of cre recombinase in the myeloid lineage. (J:109131)

Activity:	Tissue activity of this recombinase allele
Driver:	ITGAM (human) Summary of all recombinase alleles driven by ITGAM. Comparative matrix view of recombinase activities Alliance human ITGAM gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

1 RNA-Seq or microarray experiment(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:109131 Boillee S, et al., Onset and Progression in Inherited ALS Determined by Motor Neurons and Microglia. Science. 2006 Jun 2;312(5778):1389-92
All:	32 reference(s)