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Rcan1tm1Jmol
Targeted Allele Detail
Summary
Symbol: Rcan1tm1Jmol
Name: regulator of calcineurin 1; targeted mutation 1, Jeffery D Molkentin
MGI ID: MGI:3641540
Synonyms: mcip1-
Gene: Rcan1  Location: Chr16:92188839-92263057 bp, - strand  Genetic Position: Chr16, 53.6 cM
Alliance: Rcan1tm1Jmol page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:109586
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  129
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exons 5 and 6 were replaced with a neomycin resistance gene via homologous recombination. Wesetern blot confirmed absence of protein in mutant heart, skeletal muscle and brain. (J:109586)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Structures Affected by this Mutation: 2 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Rcan1 Mutation:  26 strains or lines available
References
Original:  J:109586 Sanna B, et al., Modulatory calcineurin-interacting proteins 1 and 2 function as calcineurin facilitators in vivo. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7327-32
All:  8 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory