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Csf2rb2tm1Cgb
Targeted Allele Detail
Summary
Symbol: Csf2rb2tm1Cgb
Name: colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage); targeted mutation 1, C Glenn Begley
MGI ID: MGI:3652583
Synonyms: Betail3-, BIL3-
Gene: Csf2rb2  Location: Chr15:78166707-78189921 bp, - strand  Genetic Position: Chr15, 37.22 cM
Alliance: Csf2rb2tm1Cgb page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:32978
Parent Cell Line:  W9.5/W95 (ES Cell)
Strain of Origin:  129S1/Sv-Oca2+ Tyr+ Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
    Exons 9-13 were replaced with a neomycin resistance cassette. (J:32978)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 2 strains available      Cell Lines: 0 lines available
Carrying any Csf2rb2 Mutation:  47 strains or lines available
References
Original:  J:32978 Nicola NA, et al., Functional inactivation in mice of the gene for the interleukin-3 (IL-3)-specific receptor beta-chain: implications for IL-3 function and the mechanism of receptor transmodulation in hematopoietic cells. Blood. 1996 Apr 1;87(7):2665-74
All:  19 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory