About   Help   FAQ
Ilktm3Ref
Targeted Allele Detail
Summary
Symbol: Ilktm3Ref
Name: integrin linked kinase; targeted mutation 3, Reinhard Fassler
MGI ID: MGI:3653044
Synonyms: Ilkflox
Gene: Ilk  Location: Chr7:105385799-105392132 bp, + strand  Genetic Position: Chr7, 55.97 cM, cytoband E1
Alliance: Ilktm3Ref page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110783
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A targeting vector was designed to flank exon 2 with loxP sites such that Cre-mediated recombination would ablate gene expression. (J:82761, J:110783)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ilk Mutation:  18 strains or lines available
References
Original:  J:110783 Grashoff C, et al., Integrin-linked kinase regulates chondrocyte shape and proliferation. EMBO Rep. 2003 Apr;4(4):432-8
All:  23 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory