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Ilktm3Ref
Targeted Allele Detail
Summary
Symbol: Ilktm3Ref
Name: integrin linked kinase; targeted mutation 3, Reinhard Fassler
MGI ID: MGI:3653044
Synonyms: Ilkflox
Gene: Ilk  Location: Chr7:105385799-105392132 bp, + strand  Genetic Position: Chr7, 55.97 cM, cytoband E1
Alliance: Ilktm3Ref page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:110783
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Conditional ready, No functional change)
Mutation:    Insertion
 
Mutation details: A targeting vector was designed to flank exon 2 with loxP sites such that Cre-mediated recombination would ablate gene expression. (J:82761, J:110783)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 6 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ilk Mutation:  18 strains or lines available
References
Original:  J:110783 Grashoff C, et al., Integrin-linked kinase regulates chondrocyte shape and proliferation. EMBO Rep. 2003 Apr;4(4):432-8
All:  23 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
12/10/2024
MGI 6.24 		The Jackson Laboratory