Summary | Transgene origin | Transgene description | Expression | Recombinase activity | Phenotypes | Disease models | Tumor data | Find Mice (IMSR) | References

Symbol:	Tg(TPO-cre)1Shk
Name:	transgene insertion 1, Shioko Kimura
MGI ID:	MGI:3653644
Synonyms:	TPO-cre
Transgene:	Tg(TPO-cre)1Shk  Location: unknown  Genetic Position: Chr9, Syntenic
Alliance:	Tg(TPO-cre)1Shk page

Strain of Origin:

FVB/NCr

Transgene Type:    Transgenic (Recombinase) Mutation:    Insertion   Tg(TPO-cre)1Shk expression driven by 1 gene Transgene expression driven by: Organism Driver Gene Homolog in Mouse Note human TPO (7173) Tpo  (MGI:98813)   Mutation details: This transgene expresses cre recombinase under the control of the human thyroid peroxidase gene promoter. Insulator sequences were placed upstream and downstream of the TPO-cre cassette. The insertion site was found to be between bp 12,372,316 and 12,372,324 on mouse chromosome 9, near Cntn5 and Jrkl, approximately 1.5 and 0.9 Mbp from the transgene, respectively (J:303278). (J:92293)

Activity:	Tissue activity of this recombinase allele
Driver:	TPO (human) Summary of all recombinase alleles driven by TPO. Comparative matrix view of recombinase activities Alliance human TPO gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:

2 RNA-Seq or microarray experiment(s)

List all tumor models in MMHCdb carrying Tg(TPO-cre)1Shk

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 1 strain available      Cell Lines: 0 lines available

Original:	J:92293 Kusakabe T, et al., Thyrocyte-specific expression of Cre recombinase in transgenic mice. Genesis. 2004 Jul;39(3):212-6
All:	48 reference(s)