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Igflr1 Gene Detail
Summary
  • Symbol
    Igflr1
  • Name
    IGF-like family receptor 1
  • Synonyms
    F630003I17Rik, Tmem149
  • Feature Type
    protein coding gene
  • IDs
    MGI:3655979
    NCBI Gene: 101883
  • Alliance
    gene page
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:30264852-30267387 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 18.62 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    119 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3655979
 protein coding gene Chr7:30264852-30267387 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032030
 protein coding gene Chr7:29573323-29575858 (+)
A/J MGP_AJ_G0032007
 protein coding gene Chr7:28770951-28773480 (+)
AKR/J MGP_AKRJ_G0031940
 protein coding gene Chr7:29502085-29504614 (+)
BALB/cJ MGP_BALBcJ_G0032014
 protein coding gene Chr7:28958385-28960914 (+)
C3H/HeJ MGP_C3HHeJ_G0031733
 protein coding gene Chr7:29961044-29963579 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032480
 protein coding gene Chr7:30522746-30525281 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029530
 protein coding gene Chr7:29797960-29800523 (+)
CAST/EiJ MGP_CASTEiJ_G0031067
 protein coding gene Chr7:23213792-23216323 (+)
CBA/J MGP_CBAJ_G0031699
 protein coding gene Chr7:31988721-31991256 (+)
DBA/2J MGP_DBA2J_G0031851
 protein coding gene Chr7:28499364-28501895 (+)
FVB/NJ MGP_FVBNJ_G0031808
 protein coding gene Chr7:28630235-28632770 (+)
LP/J MGP_LPJ_G0031932
 protein coding gene Chr7:29880404-29882935 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0031844
 protein coding gene Chr7:31224521-31227058 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032508
 protein coding gene Chr7:29012988-29015521 (+)
PWK/PhJ MGP_PWKPhJ_G0030791
 protein coding gene Chr7:23536720-23539255 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030626
 protein coding gene Chr7:20020966-20023481 (+)
WSB/EiJ MGP_WSBEiJ_G0031177
 protein coding gene Chr7:29400103-29402623 (+)



Homology
more
  • Human Ortholog
    IGFLR1, IGF like family receptor 1
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    IGFLR1, IGF like family receptor 1
  • Synonyms
    TMEM149
  • Links
    NCBI Gene ID: 79713
    neXtProt AC: NX_Q9H665
    UniProt: Q9H665

  • Chr Location
    19q13.12
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    5
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

No experimental evidence to support Biological Process annotation, following literature review. See J:73796.
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    712
  • Tissues
    6
  • cDNA Data
    4
  • Literature Summary
    1
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 101883 NCBI Gene Model | MGI Sequence Detail 2536 C57BL/6J ±  kb
    transcript NM_145580 RefSeq | MGI Sequence Detail 1192 C57BL/6  
    polypeptide Q3U4N7 UniProt | EBI | MGI Sequence Detail 345 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 5
      cDNA 5

      Microarray probesets 5
    References
    more
    • Summaries
      All 30
      Developmental Gene Expression 1
      Gene Ontology 3
      Phenotypes 9
    • Earliest
      J:83847 Shepard J, et al., Characterization of U2AF(6), a splicing factor related to U2AF(35). Mol Cell Biol. 2002 Jan;22(1):221-30
    • Latest
      J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    11/05/2024
    MGI 6.24     		The Jackson Laboratory