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Ints1tm1Mnkm
Targeted Allele Detail
Summary
Symbol: Ints1tm1Mnkm
Name: integrator complex subunit 1; targeted mutation 1, Manabu Nakayama
MGI ID: MGI:3663683
Synonyms: Ints1tm1Mknm, KIAA1440-
Gene: Ints1  Location: Chr5:139737037-139761429 bp, - strand  Genetic Position: Chr5, 78.8 cM, cytoband G1
Alliance: Ints1tm1Mnkm page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:111319
Parent Cell Line:  R1 (ES Cell)
Strain of Origin:  (129X1/SvJ x 129S1/Sv)F1-Kitl+
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: A sequence of 606 bp was deleted, including exons 24 and 25. Northern blot and RT-PCR of failed to detect intact transcript in mutants. (J:111319)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 10 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ints1 Mutation:  70 strains or lines available
References
Original:  J:111319 Nakayama M, et al., A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins. FASEB J. 2006 Aug;20(10):1718-20
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory