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Tg(Pcp2-cre)3Mdk
Transgene Detail
Summary
Symbol: Tg(Pcp2-cre)3Mdk
Name: transgene insertion 3, Michael D Koob
MGI ID: MGI:3664534
Synonyms: P-CRE-3
Transgene: Tg(Pcp2-cre)3Mdk  Location: unknown  
Alliance: Tg(Pcp2-cre)3Mdk page
Transgene
origin
Strain of Origin:  Not Applicable
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Pcp2-cre)3Mdk expression driven by 1 gene
 
Mutation detailsThis transgene consists of a 835 bp fragment of the purkinje cell protein 2 5' regulatory region, 1.3 kb of Cre recombinase, and 240 bp of simian virus 40 polyA signal. This transgene expresses cre specifically in Purkinje cells. A transgenic line Tg(Pcp2-cre)1Mdk was also produced but was less effective. (J:112937)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Pcp2 (species not specified)
Summary of all recombinase alleles driven by Pcp2.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
References
Original:  J:112937 He Y, et al., Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits. J Neurosci. 2006 Sep 27;26(39):9975-82
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory