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Cntnap5b Gene Detail
Summary
  • Symbol
    Cntnap5b
  • Name
    contactin associated protein-like 5B
  • Synonyms
    C230078M14Rik, Caspr5-2
  • Feature Type
    protein coding gene
  • IDs
    MGI:3664583
    NCBI Gene: 241175
  • Alliance
    gene page
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:99700490-100413667 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 48.19 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    26696 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_3664583
 protein coding gene Chr1:99700006-100418324 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016363
 protein coding gene Chr1:101607009-102391358 (+)
A/J MGP_AJ_G0016347
 protein coding gene Chr1:98185391-98898823 (+)
AKR/J MGP_AKRJ_G0016307
 protein coding gene Chr1:100860860-101623139 (+)
BALB/cJ MGP_BALBcJ_G0016303
 protein coding gene Chr1:98203529-98908423 (+)
C3H/HeJ MGP_C3HHeJ_G0016130
 protein coding gene Chr1:101208512-101948460 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016762
 protein coding gene Chr1:105605779-106365445 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014480
 protein coding gene Chr1:92364371-93044313 (+)
CAST/EiJ MGP_CASTEiJ_G0015712
 protein coding gene Chr1:100256932-101011303 (+)
CBA/J MGP_CBAJ_G0016103
 protein coding gene Chr1:109113241-109926834 (+)
DBA/2J MGP_DBA2J_G0016208
 protein coding gene Chr1:97255527-97962446 (+)
FVB/NJ MGP_FVBNJ_G0016209
 protein coding gene Chr1:96222522-96929890 (+)
LP/J MGP_LPJ_G0016282
 protein coding gene Chr1:102917602-103669462 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016235
 protein coding gene Chr1:113016890-113853216 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016801
 protein coding gene Chr1:100936207-101668836 (+)
PWK/PhJ MGP_PWKPhJ_G0015499
 protein coding gene Chr1:96403596-97115739 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015284
 protein coding gene Chr1:99729059-100463250 (+)
WSB/EiJ MGP_WSBEiJ_G0015775
 protein coding gene Chr1:100722215-101490098 (+)



Homology
more
  • Human Ortholog
    CNTNAP5, contactin associated protein family member 5
  • Vertebrate Orthologs
    6
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    CNTNAP5, contactin associated protein family member 5
  • Synonyms
    caspr5
  • Links
    NCBI Gene ID: 129684
    neXtProt AC: NX_Q8WYK1
    UniProt: Q8WYK1

  • Chr Location
    2q14.3; chr2:124025287-124921219 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    11 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    4
  • GO References
    3
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    776
  • Tissues
    24
  • cDNA Data
    6
  • Literature Summary
    2
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000067028 Ensembl Gene Model | MGI Sequence Detail 713178 C57BL/6J ±  kb
transcript ENSMUST00000086738 Ensembl | MGI Sequence Detail 4027 Not Applicable  
polypeptide ENSMUSP00000083944 Ensembl | MGI Sequence Detail 1292 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006196 contactin-associated protein like 5-2
    (term hierarchy)
  • InterPro Domains
    IPR000421 Coagulation factor 5/8 C-terminal domain
    IPR013320 Concanavalin A-like lectin/glucanase domain superfamily
    IPR000742 EGF-like domain
    IPR002181 Fibrinogen, alpha/beta/gamma chain, C-terminal globular domain
    IPR036056 Fibrinogen-like, C-terminal
    IPR008979 Galactose-binding-like domain superfamily
    IPR001791 Laminin G domain
    IPR050372 Neurexin-related cell adhesion and synaptic protein
  • GlyGen
    Q0V8T8 9 sites, 4 N-linked glycans (7 sites)
Molecular
Reagents
less
  • All nucleic 10
    cDNA 6
    Primer pair 1
    Other 3

    Microarray probesets 1
Other
Accession IDs
less
MGI:3606070
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 11
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:345621 Adams DJ, et al., Genetic determinants of micronucleus formation in vivo. Nature. 2024 Mar;627(8002):130-136
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory