Sox6 In situ reporter (knock in) Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:80666 Smits P, et al., The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001 Aug;1(2):277-90
Assay type:	In situ reporter (knock in)
MGI Accession ID:	MGI:3687049
Gene symbol:	Sox6
Gene name:	SRY (sex determining region Y)-box 6

Reporter:	lacZ
	Direct Detection

Results

Specimen 1D: embryonic day 15.5; Sox6^tm1Vlf/Sox6^tm1Vlf (more

)

Structure	Level	Pattern	Image	Note
TS23: cartilage	Present	Uniform	1D Sox6-/-
TS23: telencephalon	Present		1D Sox6-/-

Specimen 3E left: embryonic day 15.5; Sox5^tm1Vlf/Sox5^tm1Vlf, Sox6^tm1Vlf/Sox6⁺ (more

)
Note: Stained for both Sox6 and Sox5 (assay MGI:3687048) reporters.

Structure	Level	Pattern	Image	Note
TS23: embryo	Strong		3E left embryo	Expression was strong in all sites of chondrogenesis.
TS23: telencephalon	Strong		3E left embryo

Specimen 3E right: embryonic day 15.5; Sox5^tm1Vlf/Sox5^tm1Vlf, Sox6^tm1Vlf/Sox6^tm1Vlf (more

)
Note: Stained for both Sox6 and Sox5 (assay MGI:3687048) reporters.

Structure	Level	Pattern	Image	Note
TS23: embryo	Strong		3E right embryo	Expression was strong in all sites of chondrogenesis.
TS23: telencephalon	Strong		3E right embryo

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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