Rr159tm1.1Fwa
Targeted Allele Detail
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| Symbol: |
Rr159tm1.1Fwa |
| Name: |
regulatory region 159; targeted mutation 1.1, Frederick W Alt |
| MGI ID: |
MGI:3687498 |
| Synonyms: |
3'Ekappadelta, Igk-Eiktm1.1Fwa, Igktm1.1Fwa |
| Gene: |
Rr159 Location: unknown Genetic Position: Chr6, Syntenic
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| Alliance: |
Rr159tm1.1Fwa page
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| Germline Transmission: |
Earliest citation of germline transmission:
J:113715
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| Parent Cell Line: |
E14.1 (ES Cell)
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| Strain of Origin: |
129P2/OlaHsd
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| Allele Type: |
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Targeted (Modified regulatory region, Null/knockout) |
| Mutations: |
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Insertion, Intragenic deletion
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Mutation details: The loxP site flanked neomycin resistance gene cassette in place of the entire 808 bp 3' enhancer region (3'Ekappa), downstream of the Igk cluster, was removed via cre-mediated recombination.
(J:113715)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Carrying any Rr159 Mutation: |
0 strains or lines available
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| Original: |
J:113715 Gorman JR, et al., The Ig(kappa) enhancer influences the ratio of Ig(kappa) versus Ig(lambda) B lymphocytes. Immunity. 1996 Sep;5(3):241-52 |
| All: |
6 reference(s) |
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Analysis Tools
