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Nkx3-1tm1(cre)Wez
Targeted Allele Detail
Summary
Symbol: Nkx3-1tm1(cre)Wez
Name: NK3 homeobox 1; targeted mutation 1, Warren E Zimmer
MGI ID: MGI:3689997
Synonyms: Nkx3.1-cre
Gene: Nkx3-1  Location: Chr14:69428141-69432107 bp, + strand  Genetic Position: Chr14, 36.02 cM
Alliance: Nkx3-1tm1(cre)Wez page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:114573
Parent Cell Line:  AB2.2 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Recombinase)
Mutation:    Insertion
 
Nkx3-1tm1(cre)Wez expression driven by 1 gene
 
Mutation detailsA cre-PGK-neo cassette was inserted into the second exon of the locus, deleting ~630 bp spanning from the homeodomain to the end of the protein. (J:114573)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Nkx3-1 (mouse)
Summary of all recombinase alleles driven by Nkx3-1.
 

Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Nkx3-1 Mutation:  38 strains or lines available
References
Original:  J:114573 Stanfel MN, et al., Expression of an Nkx3.1-CRE gene using ROSA26 reporter mice. Genesis. 2006 Nov;44(11):550-5
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory