About   Help   FAQ
Tg(Gnrh1-cre)1Dlc
Transgene Detail
Summary
Symbol: Tg(Gnrh1-cre)1Dlc
Name: transgene insertion 1, Catherine Dulac
MGI ID: MGI:3691288
Synonyms: LHRH::Cre
Transgene: Tg(Gnrh1-cre)1Dlc  Location: unknown  
Alliance: Tg(Gnrh1-cre)1Dlc page
Transgene
origin
Strain of Origin:  (C57BL/6 x CBA)F1
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Gnrh1-cre)1Dlc expression driven by 1 gene
 
Mutation details: A cre-containing cassette including a nuclear localization signal and a polyadenylation sequence was inserted into the start codon of the LHRH gene by homologous recombination of the BAC, RP23-22J8 which includes 137 kb of 5' upstream and 73 kb downstream sequences around the LHRH coding sequence of the BAC. The modified BAC was then used to create transgenic mice. (J:115190)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Gnrh1 (mouse)
Summary of all recombinase alleles driven by Gnrh1.
 

Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 15 assay results
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
References
Original:  J:115190 Yoon H, et al., Olfactory inputs to hypothalamic neurons controlling reproduction and fertility. Cell. 2005 Nov 18;123(4):669-82
All:  36 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
11/19/2024
MGI 6.24 		The Jackson Laboratory