Tg(Myh6-Tnnt2*R92Q)1Lnwd
Transgene Detail
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| Symbol: |
Tg(Myh6-Tnnt2*R92Q)1Lnwd |
| Name: |
transgene insertion 1, Leslie A Leinwand |
| MGI ID: |
MGI:3692448 |
| Synonyms: |
30%, R92Q-Myc |
| Transgene: |
Tg(Myh6-Tnnt2*R92Q)1Lnwd Location: unknown
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| Alliance: |
Tg(Myh6-Tnnt2*R92Q)1Lnwd page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Inserted expressed sequence) |
| Mutation: |
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Insertion
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Tg(Myh6-Tnnt2*R92Q)1Lnwd expresses
1 gene
Transgene expresses:
| Organism |
Expressed Gene |
Note |
| mouse |
Tnnt2 (MGI:104597) |
Transgene codes for a protein with an arginine to glutamine mutation. |
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Mutation details: This transgene expresses a mouse Tnnt2 gene, with codon 92 mutated to encode an glutamine instead of the arginine and an 11-amino acid c-myc epitope added to the 5' end of the coding region, under the control of a rat alpha-myosin heavy chain promoter. This line expresses 30% of the total Tnnt2 as the mutant transgenic form.
(J:56911)
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View phenotypes and curated references for all genotypes (concatenated display).
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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| Original: |
J:56911 Tardiff JC, et al., Cardiac troponin T mutations result in allele-specific phenotypes in a mouse model for hypertrophic cardiomyopathy. J Clin Invest. 1999 Aug;104(4):469-81 |
| All: |
2 reference(s) |
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Analysis Tools
