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Satb2tm1Rug
Targeted Allele Detail
Summary
Symbol: Satb2tm1Rug
Name: special AT-rich sequence binding protein 2; targeted mutation 1, Rudolf Grosschedl
MGI ID: MGI:3692768
Synonyms: Satb2-, Satb2LacZ
Gene: Satb2  Location: Chr1:56833140-57017809 bp, - strand  Genetic Position: Chr1, 28.72 cM
Alliance: Satb2tm1Rug page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:115876
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
 
Mutation detailsA betagalactosidase/pgk-neo cassette was inserted in frame with the ATG codon in exon 2. Immunoblot confirmed absence of protein in mutant mice. (J:115876)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 127 assay results
1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation: 20 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Satb2 Mutation:  43 strains or lines available
References
Original:  J:115876 Dobreva G, et al., SATB2 is a multifunctional determinant of craniofacial patterning and osteoblast differentiation. Cell. 2006 Jun 2;125(5):971-86
All:  12 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory