Summary | Mutation origin | Mutation description | Expression | Recombinase activity | Phenotypes | Disease models | Find Mice (IMSR) | References

Symbol:	Satb2tm1(cre)Vit
Name:	special AT-rich sequence binding protein 2; targeted mutation 1, Victor Tarabykin
MGI ID:	MGI:3695425
Synonyms:	Satb2-
Gene:	Satb2  Location: Chr1:56833140-57017809 bp, - strand  Genetic Position: Chr1, 28.72 cM
Alliance:	Satb2tm1(cre)Vit page

Germline Transmission:	Earliest citation of germline transmission: J:116770
Parent Cell Line:	Not Specified (ES Cell)
Strain of Origin:	Not Specified

Allele Type:    Targeted (Recombinase) Mutation:    Insertion   Satb2tm1(cre)Vit expression driven by 1 gene Knock-in expression driven by: Organism Driver Gene Note mouse Satb2 (MGI:2679336)     Exon 2 was replaced with cre recombinase cDNA and a neomycin resistance cassette. (J:116770)

Activity:	Tissue activity of this recombinase allele
Driver:	Satb2 (mouse) Summary of all recombinase alleles driven by Satb2. Alliance mouse Satb2 gene page

View phenotypes and curated references for all genotypes (concatenated display).

In Mice Carrying this Mutation:	21 assay results
In Structures Affected by this Mutation:	12 anatomical structure(s)

Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:	Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Satb2 Mutation:	43 strains or lines available

Original:	J:116770 Britanova O, et al., Satb2 haploinsufficiency phenocopies 2q32-q33 deletions, whereas loss suggests a fundamental role in the coordination of jaw development. Am J Hum Genet. 2006 Oct;79(4):668-78
All:	8 reference(s)