Tg(Camk2a-cre)17NKmik
Transgene Detail
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| Symbol: |
Tg(Camk2a-cre)17NKmik |
| Name: |
transgene insertion 17N, Katsuhiko Mikoshiba |
| MGI ID: |
MGI:3697165 |
| Synonyms: |
Cre17N, TgN(a-CaMKII-nlCre)/17N |
| Transgene: |
Tg(Camk2a-cre)17NKmik Location: unknown
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| Alliance: |
Tg(Camk2a-cre)17NKmik page
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| Strain of Origin: |
Not Specified
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| Transgene Type: |
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Transgenic (Recombinase) |
| Mutation: |
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Insertion
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Tg(Camk2a-cre)17NKmik expression driven by
1 gene
Transgene expression driven by:
| Organism |
Driver Gene |
Note |
| mouse |
Camk2a (MGI:88256) |
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Mutation details: Expression of bacteriophage P1 Cre recombinase, bearing the nuclear localization signal peptide of SV40 large T antigen, is directed by the promoter of the mouse gene encoding calcium/calmodulin-dependent protein kinase II alpha. Expression of the transgene was demonstrated by RT-PCR analysis, immunoblot analysis and a reporter assay for Cre recombinase activity. Activity is present specifically in the nuclear fraction of the cerebrum, although a low level (1-10% of that in the cerebrum) of "leaky" expression is observed in the cerebellum as well.
(J:104881)
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Activity: |
 Tissue activity of this recombinase allele
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Driver:
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Camk2a
(mouse)
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| Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
| Carrying this Mutation: |
Mouse Strains: 1 strain available
Cell Lines: 0 lines available
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Of several transgenic lines created, lines 10 and 26 exhibit higher Cre recombinase expression than lines 17N, 11 and 20.
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| Original: |
J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013; |
| All: |
1 reference(s) |
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Analysis Tools
