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Tg(Camk2a-cre)20Kmik
Transgene Detail
Summary
Symbol: Tg(Camk2a-cre)20Kmik
Name: transgene insertion 20, Katsuhiko Mikoshiba
MGI ID: MGI:3697168
Synonyms: Cre20, TgN(a-CaMKII-nlCre)/20
Transgene: Tg(Camk2a-cre)20Kmik  Location: unknown  
Alliance: Tg(Camk2a-cre)20Kmik page
Transgene
origin
Strain of Origin:  Not Specified
Transgene
description
Transgene Type:    Transgenic (Recombinase)
Mutation:    Insertion
 
Tg(Camk2a-cre)20Kmik expression driven by 1 gene
 
Mutation details: Expression of bacteriophage P1 Cre recombinase, bearing the nuclear localization signal peptide of SV40 large T antigen, is directed by the promoter of the mouse gene encoding calcium/calmodulin-dependent protein kinase II alpha. Expression of the transgene was demonstrated by RT-PCR analysis, immunoblot analysis and a reporter assay for Cre recombinase activity. Activity is present specifically in the nuclear fraction of the cerebrum, although a low level (1-10% of that in the cerebrum) of "leaky" expression is observed in the cerebellum as well. (J:104881)
Recombinase
activity
Activity:
 Tissue activity of this recombinase allele
Driver: Camk2a (mouse)
Summary of all recombinase alleles driven by Camk2a.
 

Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Notes
Of several transgenic lines created, lines 10 and 26 exhibit higher Cre recombinase expression than lines 17N, 11 and 20.
References
Original:  J:104881 The RIKEN BioResource Center, Information obtained from The RIKEN BioResource Center. Unpublished. 2006-2013;
All:  3 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory