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Hmga1tm2Afus
Targeted Allele Detail
Summary
Symbol: Hmga1tm2Afus
Name: high mobility group AT-hook 1; targeted mutation 2, Alfredo Fusco
MGI ID: MGI:3697313
Synonyms: Hmga1-
Gene: Hmga1  Location: Chr17:27775471-27782648 bp, + strand  Genetic Position: Chr17, 14.5 cM
Alliance: Hmga1tm2Afus page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:117669
Parent Cell Line:  AB2.1 (ES Cell)
Strain of Origin:  129S7/SvEvBrd-Hprt1b-m2
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation details: Exons V and VI were replaced with a neomycin resistance cassette. Northern blot analysis confirmed absence of transcripts in mutant ES cells. (J:117669)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hmga1 Mutation:  23 strains or lines available
References
Original:  J:117669 Battista S, et al., Loss of Hmga1 gene function affects embryonic stem cell lympho-hematopoietic differentiation. FASEB J. 2003 Aug;17(11):1496-8
All:  2 reference(s)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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11/19/2024
MGI 6.24 		The Jackson Laboratory